CAS#:2460055-10-9
FOX04-DRI
Size
Research Profile
FOX04-DRI
Literature-based research context for laboratory reference only.
FOX04-DRI is a cell-permeable D-retro-inverso peptide designed to act as a senolytic agent by disrupting the interaction between FOXO4 and p53. In preclinical models of aging and chemotoxicity, selective disruption of this complex enables p53 to initiate cell-intrinsic apoptosis in senescent cells while leaving healthy cells unaffected, helping restore tissue homeostasis.
Selected literature
- Baar et al., 2017, Cell.
This page is provided for laboratory reference and literature review only. The material is not presented as a consumer product, medical treatment, diagnostic tool, or recommendation for human or animal use.
Overview
FOX04-DRI is presented here as a laboratory reference entry. The Research Profile summarizes literature-based biological context, while this Overview documents the identity record, specification set, preparation format, and quality-reference information available on the page.
The identity block lists CAS number 2460055-10-9, molecular formula C₂₂₈H₃₈₈N₈₆O₆₄, and molecular weight 5358.06 Da. The material record is paired with ≥99% purity information and a lyophilized presentation for reference review.
Available specification labels include 2mg and 10mg. The active selection is 2mg; changing the selector updates the visible specification label and COA lot references while preserving the same research-reference context.
For the active selection, the page currently shows 1 active COA lot reference. COA links, when present, are retained for batch-level purity, identity, and quantity review, while packaging and storage details remain separated in Structure & Identity.